This is not a normal week in America, and yet, in many ways, it is. Protesters have taken to the streets across the country and around the world to demand justice for the murders of Ahmaud Arbery, Breonna Taylor, and George Floyd, three Black Americans who have been murdered in the past month, two of... Continue Reading →
Larissa Biggers Reading time: 3 minutes A cure for a disease such as malaria, polio, or cancer is a treatment that eliminates it. A cure can work on an individual level or a group level. If a treatment is effective for a group such that no disease is left in the population, the condition is... Continue Reading →
Reading time: 5 minutes Brittany Avin McKelvey Many of us are enticed by the possibility of extending our lives, towards the goal of one day being able to live forever. This wish may be closer to becoming reality with the promise of some research in which the activation of only one enzyme, usually turned off... Continue Reading →
Sara Musetti Estimated reading time: 5 minutes It seems talking about the immune system and how it can fight cancer is all the rage these days, especially here at OncoBites. But talking about it can be tricky, especially because most people seldom think about their immune system. It’s a part of your body, but… which... Continue Reading →
Reading time: 5 minutes Aileen I Fernandez Cancer is a complex disease associated with multiple factors. To fully understand the disease and find treatments, these multiple factors should be addressed. One of the intractable layers associated with this disease is the health disparity. The disparity here refers to a greater disease burden seen in one... Continue Reading →
Reading time: 4 minutes Jessica Desamero Molecules can be portrayed as “ball-and-spring” models, where the balls are atoms and the springs are the chemical bonds that tether them. Just as a spring, the chemical bonds can be moved around in a variety of ways to cause masses to vibrate as well as move differently and... Continue Reading →
Reading time: 6 minutes Kate Secombe Have you ever thought about how the cells in our body die? There are many ways a cell can die due to both external or internal factors, playing a role in keeping the body healthy and removing dangerous cells from the body system. When cells fail to listen to... Continue Reading →
MaryAnn Bowyer Reading Time: 3 minutes When we think of cancer cells, we often imagine a mastermind cell that has somehow managed to evade all of our body’s natural defenses as well as even modern day science. However, years of scientific research and publications have shown that the “mastermind” behind this particular cell is, in... Continue Reading →
Reading time: 3 minutes Morgan McSweeney Skin melanoma is the 5th most common type of cancer in the United States. Strikingly, 1 in 5 Americans develop skin cancer by the age of 70, and an average of 2 people die from skin cancer each hour. However, if detected while the tumor is still only present... Continue Reading →
Reading time: 5 minutes Varshit Dusad Gene therapy has rapidly become one of the most promising new medical developments of our time. It has significant advantages over traditional therapies including the potential for one-time dosage instead of recurring treatment and higher specificity compared to traditional chemotherapy. Cancer is a genetic disease! It occurs when normal... Continue Reading →
Reading time: 5 minutes Prathyusha Konda For the past decade, a growing area of cancer research has been focused on cancer immunotherapies. From the Nobel prize-winning checkpoint inhibitor therapy to cancer vaccines, the idea behind immunotherapies is to boost or activate the immune system. While the therapies being developed may be new, the idea behind... Continue Reading →
Reading Time: 4 minutes MaryAnn Bowyer Reading Time: 4 minutes It is a known fact that research into cancer treatment has become difficult due to the high specificity of causes behind tumor development. Indeed, it appears that for every step forward in terms of cancer treatment there is also a slight step backward. It is... Continue Reading →
Reading time: 3 minutes Manisit Das It is a scary and anxious moment for many of us, and if you are on the internet, it is hard to miss updates about the latest coronavirus disease, COVID-19. The viral disease is characterized by flu-like symptoms and may cause respiratory infections in certain individuals, was declared a... Continue Reading →
Reading time: 3 minutes Michael Marand You may be familiar with the handy ‘Find My iPhone’ feature that comes with Apple cell phones. This feature uses radio waves from cell towers to direct you precisely to the spot where you dropped your device. Following similar principles, physicians can use imaging techniques to obtain signals from... Continue Reading →
Reading time: 4 minutes Brittany Avin McKelvey We are in a hayday for cancer therapies, as research has surpassed traditional chemotherapeutics. New drugs, new treatment regimens, and even new drug classes are approved each day, broadening the horizons of oncology. The newest types of drugs to recently gain FDA approval are tissue agnostic drugs. (See... Continue Reading →
Reading time: 5 minutes Keighley Reisenauer Breast cancer is a collection of diseases, organized into subtypes designating which treatments may be best for the patient and how aggressive the cancer is likely to be. One thing that is universal across all subtypes, though, is what makes them worse: metastasis. When cancer metastasizes, it spreads across... Continue Reading →
Reading time: 4 minutes Jordan E. Rogers, Andrew C. Griggs, Elizabeth H. Lazzara Research Engineering and Applied Collaborations in Healthcare (REACH) Lab Cancer is a prevalent disease that manifests drastically differently across individuals due to the interplay of multiple factors. Due to the disease’s multifaceted nature, the provision of safe, quality care within cancer is... Continue Reading →
Reading time: 5 minutes Aishwarya Subramanian The life cycle of cells is a key piece of our understanding of cancer; as cells grow, they divide and produce two new “daughter” cells. For the cells to divide, grow and survive, it requires energy which they gain by metabolising glucose. However, every healthy cell that divides has... Continue Reading →
Reading time: 3 minutes Alex S. Woodell The tale of the canary in the coal mine dates back to 1911, when British miners began carrying caged canaries with them underground as a means of detecting toxic gases. The idea of using canaries as an early indicator is credited to John Scott Haldane, a Scottish physiologist... Continue Reading →
Reading time: 3 minutes Rachel Cherney If you have read other articles on Oncobites, you know that cancer is a collection of many diseases, and these diseases are complex. Cancer cells don’t live on their own; rather, they live among the normal tissue cells, immune cells, and bacteria in your body. Additionally, cancer cells can... Continue Reading →
Reading time: 3 minutes Natasha Vinod In 2018, the Nobel Prize in Physiology or Medicine was awarded to the inventors of immune checkpoint blockade therapy, a “game-changing” technology that initiated a paradigm shift in cancer management. Checkpoint blockade therapy works by unleashing the immune surveillance against cancer by blocking the “natural brakes” (checkpoints) in the... Continue Reading →
Reading time: 5 minutes Patty Spears When talking to, or about patients, words matter. Words can hurt and make patients feel blame or guilt about having cancer. It’s not usually done on purpose, so with increased awareness of what words mean to patients, everyone can be a bit more conscientious about what they say and... Continue Reading →
Tushar Date Estimated Reading time: 4 minutes Cisplatin is an old, platinum based anticancer drug that kills cancer cells by damaging their DNA. Its cytotoxic (cell-killing) properties were discovered by accident in the 1960s, when Barnett Rosenberg was performing experiments to analyse the effect of electric field on bacterial growth. He observed that bacterial proliferation... Continue Reading →
Kedar Puvar Reading time: 3 minutes Much of the time, when scientists think of cancer-causing agents, they think of DNA damage. Indeed, some of the most infamous causes of cancer, such as excessive sunlight, tobacco smoke, or environmental pollutants, act by inducing mutations in key regions of our genes which can lead to effects such... Continue Reading →
Reading time: 4 minutes Sara Musetti As fancy as the many cancer therapies on the market may seem, the underlying goal for all cancer medicines is the same: kill cancer cells. Chemotherapies damage the DNA of rapidly dividing cells enough that the cells die, immunotherapies train the immune system to kill cancer cells, radiation causes... Continue Reading →
Reading time: 4 minutes Manisit Das Nanoparticles are tiny substances, about a hundred- to thousand-fold smaller than a typical cell, or about ten thousand-fold tinier than a grain of salt. In the past, we have discussed how nanoparticles are being investigated as carriers of drugs to tumors. These investigations were in part fueled by a... Continue Reading →
Reading time: 5 minutes Snehal Midge Breast cancer (BC) is the second highest cause of mortality worldwide. The standard clinical regimen for BC includes several modes of treatment such as chemotherapy, resection, radiotherapy, hormonal treatment, and receptor targeted therapy. Breast tumors often initially respond well to the combination of these strategies, allowing clinicians to proceed... Continue Reading →
Reading time: 4 minutes Sabarish Srinivasan Introduction to Human Papillomavirus Human papillomavirus (HPV) is a small, circular double-stranded DNA virus, of which there are several strains. HPV infection is the most common sexually transmitted infection (STI) in the US. Unfortunately, this infection is difficult to identify, as it is asymptomatic in the majority of cases,... Continue Reading →
Reading time: 3 minutes Alejandra Canales Finding treatments for lung cancer is hard because, simply-put, cancerous cells are extremely stubborn, and patients with non-small cell lung cancer can often acquire resistance to a treatment regimen. Researchers have been exploring the feasibility of “liquid biopsies,” whereby a non-invasive blood sample could be used to obtain information... Continue Reading →
Reading time: 4 minutes Aishwarya Subramanian At Oncobites we've covered the exciting emerging field of immunotherapy to treat cancer, some of which include PROTACs and BiTE molecules . Recently, significant advances have been made when trying to come up with cutting edge ideas for cancer treatment. With the recent changes in the landscape of cancer... Continue Reading →
