Reading time: 4 minutes Jessica Desamero With cancer, the environment that surrounds a tumor, or the tumor microenvironment (TME), can be just as important as the tumor itself in terms of cancer progression and drug resistance. How can this be? First, let’s take a look at what the TME is composed of. In a tumor... Continue Reading →
Mind the Gap? Filling the gaps in understanding of nanoparticle entry into tumors
Reading time: 4 minutes Manisit Das Nanoparticles are tiny substances, about a hundred- to thousand-fold smaller than a typical cell, or about ten thousand-fold tinier than a grain of salt. In the past, we have discussed how nanoparticles are being investigated as carriers of drugs to tumors. These investigations were in part fueled by a... Continue Reading →
Understanding how monoclonal antibody therapies work in solid tumors
Reading time: 4 minutes Zoey Tang In the world of anticancer therapy, there are a lot of drugs that belong to a class of proteins called monoclonal antibodies (mAbs) These Y-shaped proteins can tightly hug other proteins- including disease targets on tumor cells- with both of their arms, making the tumor cells die. Moreover, unlike... Continue Reading →