Reading time: 4 minutes Tala Tayoun A liquid biopsy test is a simple laboratory test done to sample and analyze non-solid patient biological tissue, i.e. blood. The era of liquid biopsy has revolutionized the field of cancer management. Over the last few years, we have witnessed significant technological advances in the detection and characterization of... Continue Reading →
Peering Into the Future: Where Contact Lenses May Detect Cancer
Reading time: 7 minutes Michael Marand In short-distance track competitions, the winner of a race is largely determined by how well the runners take off from the starting blocks. With the athletes only narrowly separated by their top speeds, the initial difficulty of shifting from an immobile crouch to rapid acceleration is an art that... Continue Reading →
Mass Spectrometry Advances in Oncology
Reading time: 5 minutes Susan Egbert As technology has been advancing exponentially over the years, more efficient diagnostic tools have been developed for cancer detection. Recent studies1,2,3 have shown the need for this advancement, as current diagnostic tools are still not adequate enough to detect cancer. One of the new tools that have been advancing,... Continue Reading →
AI and Oncology: An Unexpected but Useful Pairing
Reading time: 4 minutes Susan Egbert Did you know that researchers are trying to integrate artificial intelligence (AI) with cancer treatments? There are plenty of studies in oncology available that range from diagnostic to treatment that are peer-reviewed (experts looking at the articles before publishing). This is useful for AI as the more data that... Continue Reading →
Should We Rely on Robot Radiologists?
Reading time: 3 minutes Nisitha Sengottuvel Can robots accomplish the work of doctors? Some aspects of medicine may be better left to technology: one example includes the reading of mammograms to diagnose breast cancer. Thus far in the history of Oncobites, we have examined various aspects of diagnostics such as molecular vibrations, gold nanoparticles, biomarkers... Continue Reading →
Knowing the Result Before the Test – ‘zAavatars’ Predicting Therapeutic Responses in Cancer Patients
Estimated reading time: 3 minutes Darshak Bhatt Wouldn’t it be nice if a cancer patient was given therapy only if it was going to work? Although it seems like a no-brainer, many patients undergo therapy without knowing how good the chances are for a successful outcome. Reasons for this uncertainty depend on the type and... Continue Reading →
Progress in Screening: The Key To Lower Colorectal Cancer Mortality
Reading time: 6 minutes Kate Gavaghan Colorectal cancer (CRC) is the third most common form of cancer in the US, and the second most common cause of cancer death. It’s estimated that in 2020, approximately 148,000 individuals were diagnosed with CRC and about 53,200 died. The good news is that the incidence of CRC has... Continue Reading →
The circulating tumor DNA: a promising cancer biomarker
Reading time: 6 minutes Aishat Motolani What if I say a floating DNA in the blood could broadcast a glimpse of a diseased system’s future, particularly that of cancer? Diagnosing cancer commonly involves the use of invasive procedures, such as tumor tissue biopsy. This involves the examination of tissues extracted from a primary or metastatic... Continue Reading →
Closing the Gap: At-Home Cancer Tests Reduce Health Disparities in Cervical Cancer
Estimated reading time: 6 minutes Sara Musetti It is shocking to absolutely no one that there are large disparities in health care outcomes associated with socioeconomic status. As Morgan McSweeney recently wrote for OncoBites, melanoma patients on Medicaid or without access to health insurance wait longer for doctor’s visits and have poorer outcomes than patients... Continue Reading →
This Rapid Cancer Test is as Easy as: Inhale, Exhale
Michael Marand Reading time: 3 minutes Albert Einstein famously said, “If I had an hour to solve a problem, I’d spend 55 minutes thinking about the problem and 5 minutes thinking about the solutions.” While more robust cancer treatments are indubitably necessary, cancer detection is a crucial part of providing effective patient care. Early detection... Continue Reading →
AACR 2020 Dispatches Part One: Examining cancer under a new molecular lens
Reading time: 5 minutes Emily Costa Every spring, researchers, oncologists, policymakers, journalists, advocacy groups, and patients from around the globe gather at AACR, a scientific conference hosted by the American Association for Cancer Research and the largest of its kind. Matching this spectrum of attendees, the conference’s programming covers a wide array of cancer-related topics,... Continue Reading →
What is my disease condition?
Significance of Minimal Residual Disease Reading time: 3 minutes Aishwarya Subramanian Leukemia is a condition in which the number of white blood cells increase because of malfunctions in blood-forming tissues. White blood cells that provide immunity to the body and protect it from diseases undergo genetic alterations and mutations causing them to undergo rapid division.... Continue Reading →
The capability of companion diagnostics for selecting patients for immunotherapy
Reading time: 4 minutes Aileen I Fernandez When a foreign substance such as a cancer cell presents itself in the human body, it is able to communicate with cells of the human immune system. The cancer cell signals the immune system, telling it “Hey! Pump the brakes!”, thus instructing the immune system to not kill... Continue Reading →
Probing Molecular Vibrations For Cancer Diagnosis
Reading time: 4 minutes Jessica Desamero Molecules can be portrayed as “ball-and-spring” models, where the balls are atoms and the springs are the chemical bonds that tether them. Just as a spring, the chemical bonds can be moved around in a variety of ways to cause masses to vibrate as well as move differently and... Continue Reading →
Shedding some blood for cancer cure
Reading time: 5 minutes Snehal Midge Breast cancer (BC) is the second highest cause of mortality worldwide. The standard clinical regimen for BC includes several modes of treatment such as chemotherapy, resection, radiotherapy, hormonal treatment, and receptor targeted therapy. Breast tumors often initially respond well to the combination of these strategies, allowing clinicians to proceed... Continue Reading →
Gold Nanoparticles – The future of cancer diagnosis and therapy?
Reading time: 5 minutes Garima Khanna Figure 1: Gold Nanoparticles Gold nanoparticles (GNPs) possess exceptional characteristics, including high surface area to volume ratio, easy synthesis, surface chemistry, multi functionalization, stable nature and surface plasmon resonance. Because of these unique properties, they are emerging as a powerful tool for early tumor diagnosis and chemotherapeutic drug delivery... Continue Reading →
Tomosynthesis: The Latest in Breast Cancer Imaging
Reading time: 4 minutes Taylor A. Johnson Here at OncoBites, we have covered multiple advancements in the imaging and diagnosis of cancer. These have included isotonic labeling to detect the cancer progression, liquid biopsies for uncovering tumor profiles, and even artificial intelligence for interpreting images. In addition, several aspects of breast cancer, ranging from new... Continue Reading →
Sniffing out Cancer
Reading time: 4 minutes Rachel Cherney Early cancer detection is critical for increasing patient survivability; however, current methods for early detection are costly and often inaccurate. It is of great importance to find other, more cost effective and accurate methods for early cancer detection, and to do this, we may need to turn to new... Continue Reading →
Early Detection of Pancreatic Cancer: Did we figure out the warning signs?
Reading time: 3 minutes Manisit Das Pancreatic Cancer remains one of the few cancers against which we haven’t found a treatment that offers long-term benefit. Currently, less than one in ten patients will survive five years past the point of diagnosis. Like any other cancer, early diagnosis can improve treatment options and patient survivability. However,... Continue Reading →
Robots are coming for your job (if you are a radiologist)
Reading time: 4 minutes Morgan McSweeney What can humans do better than robots? For most of history, the answer to that question has been.. everything. However, the balance of power is rapidly shifting away from warm, fleshy, humans toward cold, calculating, processing power. Did you know that a few years ago, an artificial intelligence (AI)... Continue Reading →
Making cancer therapy smarter
Sara Musetti Last week on OncoBites, Beth Rogoski of PhDoodles shared with us the story of liquid biopsies, blood tests that can be used to detect cancer and evaluate treatments. Today, in a follow-up piece, we’ll go into more detail as to what technologies are making their way to market, how liquid biopsies can be... Continue Reading →
Beth Rogoyski Most would consider a blood test a bit of a pain in the arm, but except for the fantastically needle-phobic, generally not something that would keep you awake at night. Contrast that to the sentiments that spring to mind when you hear the word chemotherapy, and the two couldn’t seem more dissimilar. Despite... Continue Reading →