Reading time: 5 minutes Patty Spears The applause was thunderous and traveled like a wave across the large auditorium at the end of a 2022 American Society of Clinical Oncology (ASCO) Annual Meeting Plenary Session talk. It did not stop. The audience stood and kept applauding and reveling in the positive results of a clinical... Continue Reading →
Reading time: 5 minutes Patty Spears There are many barriers keeping patients out of clinical trials, even if they want to join the clinical trial. There are multiple steps along the way and each step is a hurdle for patients. A patient must first have physical access to the trial (structural barrier). For example, I... Continue Reading →
Reading time: 3 minutes Varshit Dusad Randomized controlled clinical trials (RCTs) are an important part of medical studies. Properly supervised trials act as the source of evidence for the safety and efficacy of new drugs, therapies, and medical devices. Hence, it is imperative that clinical trials are designed, conducted, and analysed in a robust and... Continue Reading →
Reading time: 6 minutes Varshit Dusad Oncology is a vibrant research area with many exciting discoveries unfolding every year, each emerging from research labs all over the world. However, the road from innovations in the lab to successful commercial realization in the real world is long and challenging. For a new therapy and drug to... Continue Reading →
Reading time: 5 minutes Bekah Schulz The Food and Drug Administration (FDA) is often criticized by patient advocacy groups for taking too much time to approve life-saving drugs. However, the FDA is a difficult situation; if they approve a drug too quickly and it turns out to be unsafe/ineffective, then people are upset. If they... Continue Reading →
Reading time: 4 minutes Manisit Das In the past, we have discussed checkpoint inhibitors - therapies that block communication between cancer and immune cells, preventing cancer cells from evading the immune system. Dr. James Allison and Dr. Tasuku Honjo, who won the Nobel Prize in Medicine in 2018 for their pioneering work in cancer immunotherapy... Continue Reading →
Reading time: 4 minutes Swetha Srinivasan Cancer therapies, like all other medicines, only make their way to patients after the completion of a lengthy process of extensive research studies involving animals and then people to make sure that the benefits of the drug outweigh the risks. These final research studies in people are commonly known... Continue Reading →
Manisit Das Not long ago Tamara mentioned in her OncoBites article that it is often hard to determine what factors drive cancer. Even after a mutation responsible for fueling cancer growth is identified, we do not always know how that mutation contributes to tumor formation. Understanding these mechanisms is however quite important. As we gain... Continue Reading →
Manisit Das Since the beginning of OncoBites, we’ve talked a lot about immunotherapy: using our own immune cells to destroy the cancer cells? We can’t get enough of it! In one post, we highlighted a revolutionary approach recently approved by the US Food and Drug Administration (FDA) using genetically modified immune cells to fight cancer,... Continue Reading →
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