Reading time: 4 minutes Vicky Tan Cancer severity and therapy responses can be influenced by both the cell of origin and its location. Melanoma is a skin cancer that arises from pigment-producing cells, called melanocytes. Melanoma is predicted to become the third most commonly diagnosed cancer in Australia, while in the US, 100,000 new cases... Continue Reading →
The road not taken – Cancer cells adore a lymphatic detour to avoid being ‘ferried’ to death
Darshak Bhatt Reading time: 4 minutes Migration is tough! The International committee for the Red Cross states that “… on their journey, migrants face multiple risks and high degree of vulnerability”, and adds “Thousands (of migrants) die or disappear along the way every year.” Similarly, a cancer cell faces challenges related to migration and the... Continue Reading →
How cancer cells dodge targeted “silver bullet” treatments: BRAF/MEK resistance in melanoma
Reading time: 5 minutes Chris Wang Like Keanu Reeves dodging bullets within The Matrix, cancer cells can dodge even carefully designed anti-cancer agents. Scientists strive to design “silver bullets,” ones which target cancer cells while sparing healthy normal cells. This "silver bullet" approach is appealing to researchers due to the promise of improved therapeutic response... Continue Reading →
Melanoma patients with private insurance are diagnosed earlier than those with Medicaid or no health insurance
Reading time: 3 minutes Morgan McSweeney Skin melanoma is the 5th most common type of cancer in the United States. Strikingly, 1 in 5 Americans develop skin cancer by the age of 70, and an average of 2 people die from skin cancer each hour. However, if detected while the tumor is still only present... Continue Reading →
Repurposing existing vaccines for cancer treatment
Reading time: 5 minutes Prathyusha Konda For the past decade, a growing area of cancer research has been focused on cancer immunotherapies. From the Nobel prize-winning checkpoint inhibitor therapy to cancer vaccines, the idea behind immunotherapies is to boost or activate the immune system. While the therapies being developed may be new, the idea behind... Continue Reading →
Immune cells work together to enable successful cancer therapy
Morgan McSweeney A group of researchers from the University of California - San Francisco recently found that the presence of a certain group of immune cells in tumors (“stimulatory dendritic cells,” or SDCs) can predict better cancer outcomes, at least in melanoma patients. For example, in patients treated with checkpoint inhibitors (drugs that work by... Continue Reading →