Reading time: 5 minutes Diana Moreira The need for new and improved anti-tumor therapies has led the research field to implement different strategies to reduce, and ideally cease, tumor development. With growing publications in the field of cancer metabolism in recent years, different tumor vulnerabilities are being uncovered, increasing the likelihood of finding new therapeutic... Continue Reading →
Cancer Cell Metabolism: A Potential Therapeutic Target
Reading time: 5 minutes Aishwarya Subramanian The life cycle of cells is a key piece of our understanding of cancer; as cells grow, they divide and produce two new “daughter” cells. For the cells to divide, grow and survive, it requires energy which they gain by metabolising glucose. However, every healthy cell that divides has... Continue Reading →
Fasting Away Tumors (With a Little Help From Metformin)
Reading time: 4 minutes Sara Musetti The world of drug discovery is a frustrating, delicate world. Scientists spend years working on fine-tuning molecules to improve their function, make them safer, or even just make them easier to give to patients. We have a catalog of drugs that work on single, specific proteins only found in... Continue Reading →
Searching for the Switch: How Cancer Cells Become Drug-Resistant
Reading time: 4 minutes Sara Musetti Picture this: You walk into a strange room. Maybe you’re at a friend’s house, or the restroom in a new coffee shop, or a hotel room. It’s dark, and you can’t see, but no matter where you put your hand, you just can’t find the light switch. You know... Continue Reading →
Isotopic labeling: A peek inside cancer cells
Reading time: 4 minutes Varshit Dusad Studying the growth of the tumor is very important to devise an effective treatment against cancer. Often cancer tissues are buried deep inside the body and we need diagnostic methods that can tell us about their progression accurately without harming the body while not losing the accuracy. Therefore, invasive... Continue Reading →
The curious case of cancer metabolism
Varshit Dusad Methotrexate is one of the earliest drug discovered for treatment of cancer. It is listed by WHO as one of the essential medicines and has been used to treat various forms of cancer. Methotrexate has had such broad success across cancer subtypes due to its unique mechanism of action. Inside tumors, it attacks... Continue Reading →