Reading time: 5 minutes Michael Marand From a young age, we are taught to protect ourselves from germs. From scrubbing our teeth to washing our hands, the hygienic routines we learned as kids help us steer clear of harmful single-celled organisms. And for good reason – research suggests bacterial infection is a significant risk factor... Continue Reading →
Running Interference in Brain Cancer
Reading time: 4 minutes Anthony (Tony) Tao Controlling the genes encoded by our DNA has always been a dream in oncology. Just as our healthy cells rely on genes to properly function, cancer cells depend on our genes to thrive and parasitize our bodies. In the late 90s, a powerful technology was developed called RNA... Continue Reading →
Mind the Gap? Filling the gaps in understanding of nanoparticle entry into tumors
Reading time: 4 minutes Manisit Das Nanoparticles are tiny substances, about a hundred- to thousand-fold smaller than a typical cell, or about ten thousand-fold tinier than a grain of salt. In the past, we have discussed how nanoparticles are being investigated as carriers of drugs to tumors. These investigations were in part fueled by a... Continue Reading →
Gold Nanoparticles – The future of cancer diagnosis and therapy?
Reading time: 5 minutes Garima Khanna Figure 1: Gold Nanoparticles Gold nanoparticles (GNPs) possess exceptional characteristics, including high surface area to volume ratio, easy synthesis, surface chemistry, multi functionalization, stable nature and surface plasmon resonance. Because of these unique properties, they are emerging as a powerful tool for early tumor diagnosis and chemotherapeutic drug delivery... Continue Reading →
Falling through the gaps: Do nanoparticles enable cancer cells to escape through leaky vessels?
Reading time: 3 minutes Manisit Das Previously at Oncobites, we discussed how small particles such as nanoparticles could be used for delivering drugs against cancer. The nanoparticles can carry the drugs to the tumor taking advantage of the leakiness of blood vessels running through the tumor. The leaky vessels allow the drug-carrying nanoparticles to enter... Continue Reading →
Patterns in combat: Using old cues in the battle against cancer
Reading time: 5 minutes Manisit Das As humans, we are naturally programmed to recognize patterns. They help us detect cues in our surroundings and aid our decision making. We associate camouflage patterns with battle dress, assortments of red and green with the holidays; these recognition events help us to put things in boxes in our... Continue Reading →
Cancer and Vascular Permeability
Reading time: 5 minutes Yitong Li One of the biggest hurdles that stall new developments in cancer therapy is how to effectively deliver the treatment to the tumor. Most commonly, pharmaceutical agents and immunotherapies make their way to the tumor via the bloodstream. Hence, the successful emigration of these agents out of the blood vessels... Continue Reading →
Cancer-Curing Light
Sara Musetti The story of cancer is almost as old as the story of humans. As far back into ancient times as the 15th century BCE in Egypt, physicians have struggled to offer their patients any sort of relief from slowly spreading tumors. If tumors were visible to the naked eye--on the skin, breasts, neck,... Continue Reading →