Patterns in combat: Using old cues in the battle against cancer

Reading time: 5 minutes Manisit Das As humans, we are naturally programmed to recognize patterns. They help us detect cues in our surroundings and aid our decision making. We associate camouflage patterns with battle dress, assortments of red and green with the holidays; these recognition events help us to put things in boxes in our …

Profiling the killer: Using gene sequencing to guide management in pancreatic cancer

Manisit Das In earlier OncoBites articles, we discussed how genetic testing is increasingly used to guide cancer management. Cancer arises due to changes in our DNA sequences that make up our genes, which we refer to as gene mutations. By analyzing the genetic signatures within the tumor, clinicians can make better-informed choices to streamline the …

Feeling the ‘heat’ from neighbors: Microenvironment driving cancers in the gut

Manisit Das Not long ago Tamara mentioned in her OncoBites article that it is often hard to determine what factors drive cancer. Even after a mutation responsible for fueling cancer growth is identified, we do not always know how that mutation contributes to tumor formation. Understanding these mechanisms is however quite important. As we gain …

Stumbling before the beast: Not all cancer clinical trials end in drug approval

Manisit Das Since the beginning of OncoBites, we’ve talked a lot about immunotherapy: using our own immune cells to destroy the cancer cells? We can’t get enough of it! In one post, we highlighted a revolutionary approach recently approved by the US Food and Drug Administration (FDA) using genetically modified immune cells to fight cancer, …