An Aspirin a Day Keeps Cancer Away

Reading time: 5 minutes Alex S. Woodell Most of us have taken acetylsalicylic acid at some point in our lives. This popular drug was first brought to market in 1899 by Bayer who coined the brand name Aspirin. Aspirin belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) which are used to... Continue Reading →

Isotopic labeling: A peek inside cancer cells

Reading time: 4 minutes Varshit Dusad  Studying the growth of the tumor is very important to devise an effective treatment against cancer. Often cancer tissues are buried deep inside the body and we need diagnostic methods that can tell us about their progression accurately without harming the body while not losing the accuracy. Therefore, invasive... Continue Reading →

Biological Sex and Brain Cancer

Reading time: 5 minutes Sara Musetti If someone were to ask you whether biological sex is related to the risk of cancer, you would might say yes--cis men can suffer from prostate and testicular cancer while cis women may suffer from cervical and ovarian cancer (and are at higher risk of breast cancer). Those all... Continue Reading →

The Many Faces of Tumor Scavenging

Reading time: 8 minutes Alex S. Woodell Prologue   The tumor microenvironment (TME) is a desolate place. Nutrients are sparse, and living conditions are hostile for the resident cells. This poorly perfused, alien landscape is filled with leaky, tortuous vessels. The interstitial fluid pressure is high, severely compromising nutrient delivery mechanisms. It’s not a place... Continue Reading →

Bacteria in Cancer therapy: Friend or Foe?

Reading time: 5 minutes Varshit Dusad Bacteria are our unallied neighbors, which depending upon circumstances chooses to be our friend or foe. While bacteria such as E.coli have often been the workhorses for molecular biology studies, they have other uses as well. Surprisingly, they have enormous potential for cancer therapy. No, I am not talking... Continue Reading →

Cancer and Vascular Permeability

Reading time: 5 minutes Yitong Li One of the biggest hurdles that stall new developments in cancer therapy is how to effectively deliver the treatment to the tumor. Most commonly, pharmaceutical agents and immunotherapies make their way to the tumor via the bloodstream. Hence, the successful emigration of these agents out of the blood vessels... Continue Reading →

Players in Cancer Metastasis and Relapse

Reading time: 5 minutes Rachel Cherney Patients with metastatic cancer usually have a lower survival rate than patients without metastatic cancer, so it is important to understand how metastatis occurs, so we can learn how to improve patient survivability. Metastatic cancer makes up about 90% of cancer deaths. Cancer metastasis occurs when tumor cells break... Continue Reading →

Are humans immune to CRISPR/Cas9 gene editing?

Reading time: 4 minutes Morgan McSweeney CRISPR-Cas9 is the molecular gene editing system that has inspired hopes for a solution to genetic disease. By studying how bacteria use the CRISPR-Cas system to defend themselves against bacteriophages (viruses that infect bacteria), scientists have developed methods to use those same molecular scissors to cut out human genes... Continue Reading →

Double agents save the day?

Reading time: 6 minutes Manisit Das Sometimes double agents can be critical players in changing the course of conflicts, wars, and history. If you are a Potterhead like me, you are probably aware of how Professor Severus Snape played an important role in the wizarding world of Harry Potter. He instigated many of the major... Continue Reading →

The Sweet Method of Cancer Detection

Kaye Alcedo Time is of the essence when it comes to the battle with cancer. Detecting tumors at an early stage increases the chance of patient survival to more than 80%. However, despite today’s advancing technology, about 48% of patients get diagnosed at a very late stage. This is because screening methods of many, if... Continue Reading →

A CAR-T therapy without the T-cells

Varshit Dusad Imagine a dystopian world. Here, some citizens of an otherwise well-functioning state have gone rogue and are running an anti-national agenda. They are always plundering the natural resources meant to be evenly distributed among the population. They are quite cunning as they start slowly by deviating from the laws of their natural order... Continue Reading →

Vaccines as Cancer Prevention and Therapies

Rachel Cherney Cancer is a complex set of diseases, characterized by uncontrolled growth and metastasis, destroying important organs and bodily systems. It can occur in almost any part of the body, and in most cases, it is impossible to determine how or when it will develop, certain genetically linked cancers perhaps being an exception. Because... Continue Reading →

The Reproducibility Crisis

Morgan McSweeney As Alex Woodell recently described, the preclinical research community is in a quiet crisis. Somewhere between 50% and 90% of results from early-stage academic cancer research are unable to be reproduced by industry scientists. Studies by several large multinational pharmaceutical companies and a number of other independent research groups have confirmed what they... Continue Reading →

Create a website or blog at WordPress.com

Up ↑