It takes two brakes to stop cancer?

Reading time: 4 minutes Manisit Das In the past, we have discussed checkpoint inhibitors - therapies that block communication between cancer and immune cells, preventing cancer cells from evading the immune system. Dr. James Allison and Dr. Tasuku Honjo, who won the Nobel Prize in Medicine in 2018 for their pioneering work in cancer immunotherapy... Continue Reading →

The Rehabilitation of Thalidomide

Reading time: 4 minutes You may have heard of the infamous thalidomide, a morning sickness drug that was patented in the 1950s. Its potent anti-nausea effects made it ideal as a remedy for morning sickness in pregnant women and thalidomide was sold in over 40 countries, going as far as to be made available over... Continue Reading →

Natural Products for cancer research

Reading time: 3 minutes Bekah Schulz Natural products, or compounds isolated from plants/microorganisms, have been used as herbal medicines throughout human history. These compounds have many measurable effects. In fact, ⅓ of the top selling pharmaceuticals are natural products or their derivatives. Many antibiotics were discovered from screening these compounds and recently have shown efficacy... Continue Reading →

Evolution of chemotherapy: A look back in time

Reading time: 5 minutes Payal Yokota Chemotherapy (chemo) can be prescribed alone and in combination with other therapies such as surgery, radiation, and immunotherapies (ie. vaccines, checkpoint blockade, etc).  Since its discovery, the chemo field has greatly advanced, both in its development and ability to treat cancers. While surgery and radiation act locally to remove... Continue Reading →

Players in Cancer Metastasis: Part Two

Reading time: 4 minutes Shaye Hagler            For those of you whose lives have been impacted by cancer, you might have heard of the term “metastasis.” We call cancer metastatic when it breaks off from the initial tumor and travels to other organs. You might also have heard it being referred to before as “stage 4... Continue Reading →

Going on the offense: PROTACs as cancer therapy

Reading time: 3 minutes Kedar Puvar Diseases are typically caused by defective or malicious proteins. Traditionally, treatments for these diseases use a strategy of inhibition - use a small molecule that can block the offending protein from carrying out its function and thereby, bring things back to normal. But what if we went one step... Continue Reading →

Can exercise prevent cancer recurrence?

Reading time: 3 minutes Bekah Schulz It is well accepted that exercise is beneficial for human health and boosts overall energy level. However, the questions remains: can exercise be used as a cancer therapy? Research is indicating that it can. Over the past 20 years, studies have demonstrated that exercise decreases the risk of recurrence... Continue Reading →

Towards Personalized Cancer Medicine for All

Reading time: 6 minutes Rachel Cherney Modern medicine has saved millions of lives, but with a little improvement, it could save even more. Our current medical practices rely on medical professionals reacting to a diagnosis, treating patients after they may be or already are ill. We are increasingly recognizing the necessity of being proactive in... Continue Reading →

Overcoming the Limitations of CAR-T Therapy: Burnout

Reading time: 4 minutes Alex S. Woodell Marathon runners are an interesting breed. In order to complete the grueling 26.2 mile circuit, they must push their mental and physical boundaries to the limit. Seasoned runners possess great strength, focus, resilience, and determination. Each of these qualities is a testament to the intense training schedules they... Continue Reading →

Maternal Cancer and its Impact on Infants

Reading time: 4 minutes Varshit Dusad Cancer by no stretch of the imagination is a rare disease. It affects a significant population worldwide, and every year millions of dollar are spent investigating the causes of cancer and searching for a potential cure. However, a rarely discussed topic is the adverse impact on the health of... Continue Reading →

The Cardiac-Cancer Connection

Reading time: 3 minutes Taylor A. Johnson February is Heart Month, wherein various organizations such as the American Heart Association and the National Institute of Health raise heart health awareness and promote practices that can lower heart disease or cardiovascular disease (CVD) development. CVD and cancer are unfortunately two of the primary causes of death... Continue Reading →

An Aspirin a Day Keeps Cancer Away

Reading time: 5 minutes Alex S. Woodell Most of us have taken acetylsalicylic acid at some point in our lives. This popular drug was first brought to market in 1899 by Bayer who coined the brand name Aspirin. Aspirin belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) which are used to... Continue Reading →

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