Bacteria in Cancer therapy: Friend or Foe?

Reading time: 5 minutes Varshit Dusad Bacteria are our unallied neighbors, which depending upon circumstances chooses to be our friend or foe. While bacteria such as E.coli have often been the workhorses for molecular biology studies, they have other uses as well. Surprisingly, they have enormous potential for cancer therapy. No, I am not talking …

Players in Cancer Metastasis and Relapse

Reading time: 5 minutes Rachel Cherney Patients with metastatic cancer usually have a lower survival rate than patients without metastatic cancer, so it is important to understand how metastatis occurs, so we can learn how to improve patient survivability. Metastatic cancer makes up about 90% of cancer deaths. Cancer metastasis occurs when tumor cells break …

When good cells go bad: White blood cells may aid in tumor recurrence

Reading time: 4 mins Sara Musetti “I lit up like a Christmas tree, Hazel Grace.” This line, from John Green’s bestselling novel The Fault in Our Stars, hits hard. A young teenage survivor of cancer has had a widespread relapse picked up in one of his many routine scans since going into remission years earlier. …

Hold the sugar: identifying the contributions of high blood glucose to poor cancer outcomes

Tamara Vital We’ve talked at Oncobites about how many factors can cause or contribute to cancer. We’ve discussed how tumors arise from cells that have acquired mutations (could be inherited). Many of these factors have been related to external exposures like UV exposure from the sun or cigarette smoking that cause mutations that contribute to …

When math meets lab: The power of modeling in cancer biology

Varshit Dusad 'All models are wrong, some are useful!' - George Box The advancement of biological research relies on understanding how the different moving parts interact with each other, forming an integrated system. To better understand a system we often resort to models which help us develop a logical framework of these interactions, offering us …