Reading time: 6 minutes Brittane L. Strahan MSN, RN, CCRP The treatment of solid tumors is evolving constantly and rapidly in the vast oncology clinical research landscape. Though huge strides have been made in the treatment of even difficult tumor types (such as small cell lung cancer), there is still much work left to do.... Continue Reading →
CAR-Macrophages: The Next Step in Solid Tumor Immunotherapy?
Reading time: 4 minutes Shan Grewal Cancer has long been a formidable adversary in the world of medicine, but recent advancements in the field of immunotherapy have offered new hope in the battle against this complex disease. Immunotherapy is a revolutionary approach that harnesses the body's immune system to target and eliminate cancer cells. One... Continue Reading →
Targeting Hypoxia in Cancer Therapies: Using the Lack of Oxygen as an Advantage
Reading time: 4 minutes Jessica Desamero With cancer, the environment that surrounds a tumor, or the tumor microenvironment (TME), can be just as important as the tumor itself in terms of cancer progression and drug resistance. How can this be? First, let’s take a look at what the TME is composed of. In a tumor... Continue Reading →
Mind the Gap? Filling the gaps in understanding of nanoparticle entry into tumors
Reading time: 4 minutes Manisit Das Nanoparticles are tiny substances, about a hundred- to thousand-fold smaller than a typical cell, or about ten thousand-fold tinier than a grain of salt. In the past, we have discussed how nanoparticles are being investigated as carriers of drugs to tumors. These investigations were in part fueled by a... Continue Reading →
Understanding how monoclonal antibody therapies work in solid tumors
Reading time: 4 minutes Zoey Tang In the world of anticancer therapy, there are a lot of drugs that belong to a class of proteins called monoclonal antibodies (mAbs) These Y-shaped proteins can tightly hug other proteins- including disease targets on tumor cells- with both of their arms, making the tumor cells die. Moreover, unlike... Continue Reading →
