Reading time: 5 minutes Mahrukh Fatima Did you know that some animals, like salamanders and axolotls, can regenerate their limbs? They have this spectacular ability due to a small and rare subset of primitive cells called stem cells. These cells have the ability to differentiate into many different types of specialized cells from brain cells... Continue Reading →
Your Genetics Could Affect Your Breast Cancer Treatment
Reading time: 4 minutes Keighley Reisenauer One of the “hot button” topics right now in the cancer therapeutics industry is precision medicine. This is a practice whereby a tumor’s genetics, immune landscape, and biomarkers are compiled and evaluated holistically in order to more accurately make treatment decisions. Breast cancer especially has benefited from the targeted... Continue Reading →
Is There an App for That? Using Electronic Patient Reported Outcomes in Cancer Treatment
Reading time: 4 minutes Kate Secombe Most cancer treatments can cause side effects during or beyond treatment. While some of these side effects will not be bothersome to a person going through treatment, others may be more painful, annoying, or indicative of a problem that requires medical attention. Previous research has shown that clinicians tend... Continue Reading →
Rapalogs and Male Reproduction: Do these cancer treatments affect fertility long-term?
Reading time: 6 minutes Taylor A. Johnson Over the past few months, we have repeatedly discussed ways in which cancer may intersect with reproduction. On the female side, we have seen some of the challenges women face with fertility as well as links between bacterial infections and the development of ovarian cancer. On the male... Continue Reading →
Cannabis for Neuropathic Pain in Cancer
Reading time: 4 minutes Garima Khanna Marijuana, a popular plant cultivated throughout the globe has caught the eye of scientists to unravel the mysteries of it’s medicinal properties. The dried buds and leaves derived from Cannabis sativa and Cannabis indica have shown potential to cater pain management. While the active cannabinoid properties in marijuana have... Continue Reading →
Gene therapy vs Cancer: A promising yet challenging road
Reading time: 5 minutes Varshit Dusad Gene therapy has rapidly become one of the most promising new medical developments of our time. It has significant advantages over traditional therapies including the potential for one-time dosage instead of recurring treatment and higher specificity compared to traditional chemotherapy. Cancer is a genetic disease! It occurs when normal... Continue Reading →
Biology Guided Radiotherapy: technology to rapidly and precisely clear scattered tumors
Reading time: 3 minutes Michael Marand You may be familiar with the handy ‘Find My iPhone’ feature that comes with Apple cell phones. This feature uses radio waves from cell towers to direct you precisely to the spot where you dropped your device. Following similar principles, physicians can use imaging techniques to obtain signals from... Continue Reading →
The Power of Timing in Immunotherapy
Reading time: 3 minutes Natasha Vinod In 2018, the Nobel Prize in Physiology or Medicine was awarded to the inventors of immune checkpoint blockade therapy, a “game-changing” technology that initiated a paradigm shift in cancer management. Checkpoint blockade therapy works by unleashing the immune surveillance against cancer by blocking the “natural brakes” (checkpoints) in the... Continue Reading →
Words Matter
Reading time: 5 minutes Patty Spears When talking to, or about patients, words matter. Words can hurt and make patients feel blame or guilt about having cancer. It’s not usually done on purpose, so with increased awareness of what words mean to patients, everyone can be a bit more conscientious about what they say and... Continue Reading →
Paying for cancer care: a primer on the Oncology Care Model
Reading time: 4 minutes Swetha Srinivasan If you’ve been following the Democratic primary presidential debates, then you’re likely familiar with the spirited debate around the future of the healthcare system in the US, as well as the question: “How will we pay for it?” The world of health policy research has been evaluating on-the-ground solutions... Continue Reading →
Gold Nanoparticles – The future of cancer diagnosis and therapy?
Reading time: 5 minutes Garima Khanna Figure 1: Gold Nanoparticles Gold nanoparticles (GNPs) possess exceptional characteristics, including high surface area to volume ratio, easy synthesis, surface chemistry, multi functionalization, stable nature and surface plasmon resonance. Because of these unique properties, they are emerging as a powerful tool for early tumor diagnosis and chemotherapeutic drug delivery... Continue Reading →
Getting Cancer Treatment Right: when more is not always better
Reading time: 7 minutes Patty Spears There is a lot of effort to find new drugs to treat cancer. When a new drug works well, we all cheer when it is approved and then use the new drug the same way in all patients. Then we move to the next new drug. But, should we... Continue Reading →
PROTACs: Building better therapies
Reading time: 5 minutes Tamara Vital How do you stop an accident from happening? You could try to prevent the conditions that contribute to accidents by establishing rules that encourage and reward caution and safe behavior. On the road, licensing laws, traffic lights, and speed limits set the rules of the road, and those who... Continue Reading →
A Profile of Electric Fields in Cancer Therapeutics: Part 2- Irreversible Electroporation Therapy
Reading time: 4 minutes Michael Marand In my last article, A Profile of Electric Fields in Cancer Therapeutics, I discussed Optune System, an electric field therapy for glioblastoma that disrupts cancer cell division and results in extended patient survival. I also presented an overview of some other potential applications of electric fields in cancer therapeutics,... Continue Reading →
Two New Cancer-Fighting Compounds, Brought to You by Mushrooms
Reading time: 3 minutes Kedar Puvar At first glance, mushrooms, being immobile and nutritious, seem to be rather unassuming. Why, then, would you want to turn to mushrooms of all things as a source of new medicines? It turns out that they make up for their evolutionary weaknesses with a powerful toolbox of molecular defenses... Continue Reading →
Malignant Costs of Cancer Care
Reading time: 6 minutes Nisitha Sengottuvel So far, a lot of the articles we have been discussing here on Oncobites have been revolving around bench research regarding cancer biology and therapeutics. On the public health side of cancer care, there are a lot of emerging fields: one of which investigates the economic burden of cancer... Continue Reading →
