Anti-Angiogenic Cancer Treatments

Reading time: 5 minutes Aya Elmeligy Angiogenesis is the formation of blood vessels within the body to provide oxygen and nutrients to tissues. Tumors will hijack this process to allow for continued growth and metastasis by forming their own vascular system. Microvessel density within a tumor is often used as a prognosis tool, as the... Continue Reading →

Tumor-on-a-chip: A Better Method for Drug Discovery?

Reading time: 7 minutes Nayela Chowdhury Conventional 2D and 3D models of cancer have widely been utilized in pre-clinical drug development; however, neither of the platforms mimics the dynamic interactions that occur in living tumors. In vivo studies (for example, in small animal models)  have been central in translational cancer research and have contributed largely... Continue Reading →

‘Ubiquitous’ Ubiquitination Pathway and Cancer

Reading time: 4 minutes Deepika Jayaprakash What is common to eukaryotic organisms like animals, plants, fungi, and unicellular organisms? Ubiquitous Ubiquitin!   Ubiquitin (ub) is a small protein found in all eukaryotes that when attached to its target protein can bring about a myriad of cellular processes. The first observed effect of ubiquitination was degradation of... Continue Reading →

Non-small cell lung cancer and immunotherapy

Reading time: 4 minutes Indiwari Gopallawa Cancer is the second leading cause of death after cardiovascular diseases in the United States and has a major impact on society. Lung cancer is the second most common cancer type and is associated with lower survival rates and higher cancer-related deaths, accounting for 25% of all cancer-related deaths... Continue Reading →

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