Reading time: 4 minutes Morgan McSweeney As we have written about before, cancer immunotherapy aims to make use of the body’s own immune cells to attack cancer cells, thereby preventing their continued growth. However, the body has a system of checks and balances in place to make sure that the immune system does not accidentally... Continue Reading →
Evolution of chemotherapy: A look back in time
Reading time: 5 minutes Payal Yokota Chemotherapy (chemo) can be prescribed alone and in combination with other therapies such as surgery, radiation, and immunotherapies (ie. vaccines, checkpoint blockade, etc). Since its discovery, the chemo field has greatly advanced, both in its development and ability to treat cancers. While surgery and radiation act locally to remove... Continue Reading →
Players in Cancer Metastasis: Part Two
Reading time: 4 minutes Shaye Hagler For those of you whose lives have been impacted by cancer, you might have heard of the term “metastasis.” We call cancer metastatic when it breaks off from the initial tumor and travels to other organs. You might also have heard it being referred to before as “stage 4... Continue Reading →
Too Much Potassium Might Be Poisoning Your Anti-Tumor Immunity
Reading time: 4 minutes Sara Musetti Cancer immunotherapy has been a very hot topic here at OncoBites (because it’s a hot topic right now among cancer researchers too), but let me be super clear ⎯ it is COMPLICATED. Your immune system is balanced extremely delicately to avoid sending you into shock each time you are... Continue Reading →
Early Detection of Pancreatic Cancer: Did we figure out the warning signs?
Reading time: 3 minutes Manisit Das Pancreatic Cancer remains one of the few cancers against which we haven’t found a treatment that offers long-term benefit. Currently, less than one in ten patients will survive five years past the point of diagnosis. Like any other cancer, early diagnosis can improve treatment options and patient survivability. However,... Continue Reading →
Going on the offense: PROTACs as cancer therapy
Reading time: 3 minutes Kedar Puvar Diseases are typically caused by defective or malicious proteins. Traditionally, treatments for these diseases use a strategy of inhibition - use a small molecule that can block the offending protein from carrying out its function and thereby, bring things back to normal. But what if we went one step... Continue Reading →
Human Organ on a Chip: A Better Model for Drug Development?
Reading time: 5 minutes Kaye Alcedo Even before President Nixon’s declaration of the “war on cancer” in 1971, the journey towards a cure was nothing but a rollercoaster ride. Many promising cancer drugs are tested in human clinical trials but ultimately fail primarily because they demonstrate inadequate efficacy or safety, costing billions of dollars, increasing... Continue Reading →
Can exercise prevent cancer recurrence?
Reading time: 3 minutes Bekah Schulz It is well accepted that exercise is beneficial for human health and boosts overall energy level. However, the questions remains: can exercise be used as a cancer therapy? Research is indicating that it can. Over the past 20 years, studies have demonstrated that exercise decreases the risk of recurrence... Continue Reading →