Reading time: 5 minutes Madeline J. Morrisson Ovarian Cancer Ovarian cancer (OC) is the deadliest gynecological malignancy. High-grade serous ovarian carcinoma (HGSOC) is the most prevalent subtype of OC, with the majority of patients having late stage clinical detection. Like many types of cancer, HGSOC has both suppressive and protective immune mechanisms within the tumor... Continue Reading →
Reading time: 7 minutes Ludmila Peres Diaz, PhD The human body is a highly coordinated biological machine that responds synchronously to a wide variety of internal and external stimuli. Therefore, if one part of the body is affected, other parts will be affected to some extent, either immediately or in the distant future. If the... Continue Reading →
Reading time: 4 minutes Florence Roan In 2024, the US Food and Drug Administration (FDA) approved lifileucel for the treatment of advanced melanoma. Lifileucel’s approval marked dual milestones. It was the first tumor-infiltrating lymphocyte (TIL) therapy approved for use in cancer, and the first cellular therapy approved for a solid tumor. This new approach—using TILs... Continue Reading →
Reading time: 8 minutes Colin Ong Druggable and undruggable targets in cancer Drug discovery in cancer has always been arduous. A major milestone in aiding our understanding and discovery of cancer drugs was the advent of molecular biology. Technical advances within this field have enabled scientists to identify, dissect, and determine three-dimensional structures of tumorigenic... Continue Reading →
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