Reading time: 4 minutes Kate Secombe You may have read previously on OncoBites about immunotherapies, and the great promise they hold in treating a wide range of cancers. Commonly used immunotherapies include checkpoint inhibitors such as PD-1 or CTLA-4 inhibitors. Here I will be looking at an emerging subset of immunotherapies known as immune agonist... Continue Reading →
Is There an App for That? Using Electronic Patient Reported Outcomes in Cancer Treatment
Reading time: 4 minutes Kate Secombe Most cancer treatments can cause side effects during or beyond treatment. While some of these side effects will not be bothersome to a person going through treatment, others may be more painful, annoying, or indicative of a problem that requires medical attention. Previous research has shown that clinicians tend... Continue Reading →
Investigating the genetic basis of Graft versus Host Disease
Reading time: 5 minutes Kate Secombe The treatment for many blood cancers can be invasive and have a range of side effects. One such side-effect is known as Graft versus Host Disease (GvHD). While GvHD invokes a range of unwanted symptoms, we currently do not fully understand how and why it develops. New research by... Continue Reading →
Connections between the gut and the brain: the key to reducing pain after chemotherapy?
Reading time: 5 minutes Kate Secombe Chemotherapy-induced peripheral neuropathy (CIPN) is a relatively common side-effect of some types of chemotherapy, affecting between 19 to 85% of people. It refers to a few different conditions involving damage to the peripheral nervous system. The peripheral nervous system sends signals back to the central nervous system (brain and... Continue Reading →
Ferocious ferroptosis- programmed cell death in cancer treatment
Reading time: 6 minutes Kate Secombe Have you ever thought about how the cells in our body die? There are many ways a cell can die due to both external or internal factors, playing a role in keeping the body healthy and removing dangerous cells from the body system. When cells fail to listen to... Continue Reading →
Ulcers after Cancer Therapy – New Directions
Reading time: 5 minutes Kate Secombe Cancer treatment- it’s not fun! The treatment can take hours in the hospital, it makes you feel fatigued and has a range of difficult side-effects, including nausea, vomiting, hair loss, and memory problems. But today, I want to focus on one, in particular, mucositis, and look at the research... Continue Reading →