Reading time: 5 minutes Nayela Chowdhury Pancreatic ductal adenocarcinoma (PDAC) is an exocrine tumor of the pancreas and constitutes up to 95% of all pancreatic cancer cases. PDAC exhibits one of the poorest prognosis of all solid cancers and is associated with a very low overall and progression-free survival rate. Even though many molecular pathways... Continue Reading →
Targeting Hypoxia in Cancer Therapies: Using the Lack of Oxygen as an Advantage
Reading time: 4 minutes Jessica Desamero With cancer, the environment that surrounds a tumor, or the tumor microenvironment (TME), can be just as important as the tumor itself in terms of cancer progression and drug resistance. How can this be? First, let’s take a look at what the TME is composed of. In a tumor... Continue Reading →
Taking immunotherapy to heart: CAR-T cell therapy against cardiac fibrosis
Reading time: 4 minutes Tara Fernandez Originally designed to treat cancer, a new study shows genetically-engineered T-cells could also be a game-changer for treating heart disease. In a world first, a recent study has uncovered a new use for an approved cancer therapy - for fixing broken hearts. Researchers at the University of Pennsylvania’s Abramson... Continue Reading →
