Are Clinical Trials in Oncology Biased?

Reading time: 3 minutes Varshit Dusad Randomized controlled clinical trials (RCTs) are an important part of medical studies. Properly supervised trials act as the source of evidence for the safety and efficacy of new drugs, therapies, and medical devices. Hence, it is imperative that clinical trials are designed, conducted, and analysed in a robust and... Continue Reading →

Targeting cancer’s sweet spots

Estimated reading time: 5 minutes Payal Yokota One of the main differences between a rapidly dividing cancer cell and a normal cell is that the cancer cells rely on glycolysis followed by lactic acid fermentation, rather than oxidative phosphorylation. This effect is called the Warburg effect, one we have previously discussed in the context of... Continue Reading →

AlphaFold: A game changer in cancer?

Reading time: 4 minutes Chamath Chandrasekera Proteins are the molecular machines that perform nearly every bodily function including contracting muscles, digesting food, and healing wounds. They also provide structural support by reinforcing the shape of cells and tissues. So how do proteins go from a string of amino acids to a 3D structure with a... Continue Reading →

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