Reading time: 3 minutes Varshit Dusad Randomized controlled clinical trials (RCTs) are an important part of medical studies. Properly supervised trials act as the source of evidence for the safety and efficacy of new drugs, therapies, and medical devices. Hence, it is imperative that clinical trials are designed, conducted, and analysed in a robust and... Continue Reading →
Targeting cancer’s sweet spots
Estimated reading time: 5 minutes Payal Yokota One of the main differences between a rapidly dividing cancer cell and a normal cell is that the cancer cells rely on glycolysis followed by lactic acid fermentation, rather than oxidative phosphorylation. This effect is called the Warburg effect, one we have previously discussed in the context of... Continue Reading →
AlphaFold: A game changer in cancer?
Reading time: 4 minutes Chamath Chandrasekera Proteins are the molecular machines that perform nearly every bodily function including contracting muscles, digesting food, and healing wounds. They also provide structural support by reinforcing the shape of cells and tissues. So how do proteins go from a string of amino acids to a 3D structure with a... Continue Reading →
A Link Between Neurodegeneration and Cancer
Reading time: 5 minutes Jessica Desamero Cancer and neurodegenerative disease (a group of disorders that involve progressive degeneration of the central nervous system) are two very serious and distinct ailments. The basis of their development is distinctly different, with hallmarks of cancer centering around abnormally prolonging cell life and hallmarks of neurodegenerative disease centering around... Continue Reading →
Progress in Screening: The Key To Lower Colorectal Cancer Mortality
Reading time: 6 minutes Kate Gavaghan Colorectal cancer (CRC) is the third most common form of cancer in the US, and the second most common cause of cancer death. It’s estimated that in 2020, approximately 148,000 individuals were diagnosed with CRC and about 53,200 died. The good news is that the incidence of CRC has... Continue Reading →
