Cancer Resistance – Insights from the Animal Kingdom

 Rachel Cherney Most of us have been affected by cancer, whether we ourselves or someone we know has been diagnosed. It can be caused by various lifestyle habits, external or environmental factors, and genetics, and it’s extremely prevalent; as of 2015, 1 in 6 deaths worldwide was due to cancer. As described in a previous …

Feeling the ‘heat’ from neighbors: Microenvironment driving cancers in the gut

Manisit Das Not long ago Tamara mentioned in her OncoBites article that it is often hard to determine what factors drive cancer. Even after a mutation responsible for fueling cancer growth is identified, we do not always know how that mutation contributes to tumor formation. Understanding these mechanisms is however quite important. As we gain …

Expanding the network: new connections for an old driver in kidney cancer

Tamara Vital By now you’re probably noticing a running theme at OncoBites: cancer is complicated. Cancers have many moving parts, and despite our best efforts it can be difficult to know what factors drive them. Even when we have identified causal mutations in genes, it can be difficult to figure out how these mutations contribute …

From worms to cures

Emily B. Harrison, Ph.D Last month I attended the first RNA Therapeutics Conference held at University of Massachusetts Medical School. While I have attended several national conferences, this one beautifully encapsulated how basic science can lead to new drugs in only two decades. This conference inspired me to share with you the story of RNA …