Diet and cancer metabolism – A vulnerable axis to explore in cancer therapy

Reading time: 5 minutes Diana Moreira The need for new and improved anti-tumor therapies has led the research field to implement different strategies to reduce, and ideally cease, tumor development. With growing publications in the field of cancer metabolism in recent years, different tumor vulnerabilities are being uncovered, increasing the likelihood of finding new therapeutic... Continue Reading →

What is my disease condition?

Significance of Minimal Residual Disease Reading time: 3 minutes Aishwarya Subramanian Leukemia is a condition in which the number of white blood cells increase because of malfunctions in blood-forming tissues. White blood cells that provide immunity to the body and protect it from diseases undergo genetic alterations and mutations causing them to undergo rapid division.... Continue Reading →

Welcome to the (DNA) Neighborhood

Reading time: 3 minutes Rachel Cherney Six feet. Two meters. This is the length of DNA we have in each one of our cells. That’s almost the height of Michael Jordan! But those six feet of DNA need to fit into a tiny space that is between 5-10 micrometers. To put it into perspective, that's... Continue Reading →

Building a Highway to Tumors

Sara Musetti Estimated reading time: 5 minutes It seems talking about the immune system and how it can fight cancer is all the rage these days, especially here at OncoBites. But talking about it can be tricky, especially because most people seldom think about their immune system. It’s a part of your body, but… which... Continue Reading →

The Micro Problem with Cancer

MaryAnn Bowyer Reading Time: 3 minutes When we think of cancer cells, we often imagine a mastermind cell that has somehow managed to evade all of our body’s natural defenses as well as even modern day science. However, years of scientific research and publications have shown that the “mastermind” behind this particular cell is, in... Continue Reading →

Gene therapy vs Cancer: A promising yet challenging road

Reading time: 5 minutes Varshit Dusad Gene therapy has rapidly become one of the most promising new medical developments of our time. It has significant advantages over traditional therapies including the potential for one-time dosage instead of recurring treatment and higher specificity compared to traditional chemotherapy. Cancer is a genetic disease! It occurs when normal... Continue Reading →

Repurposing existing vaccines for cancer treatment

Reading time: 5 minutes Prathyusha Konda For the past decade, a growing area of cancer research has been focused on cancer immunotherapies. From the Nobel prize-winning checkpoint inhibitor therapy to cancer vaccines, the idea behind immunotherapies is to boost or activate the immune system. While the therapies being developed may be new, the idea behind... Continue Reading →

Cancer and CRISPR: A Promising Future

Reading Time: 4 minutes MaryAnn Bowyer Reading Time: 4 minutes It is a known fact that research into cancer treatment has become difficult due to the high specificity of causes behind tumor development. Indeed, it appears that for every step forward in terms of cancer treatment there is also a slight step backward. It is... Continue Reading →

A New Paradigm for Cancer Drug Development

Reading time: 4 minutes Brittany Avin McKelvey We are in a hayday for cancer therapies, as research has surpassed traditional chemotherapeutics. New drugs, new treatment regimens, and even new drug classes are approved each day, broadening the horizons of oncology. The newest types of drugs to recently gain FDA approval are tissue agnostic drugs. (See... Continue Reading →

Human Factors and Cancer Care

Reading time: 4 minutes Jordan E. Rogers, Andrew C. Griggs, Elizabeth H. Lazzara Research Engineering and Applied Collaborations in Healthcare (REACH) Lab Cancer is a prevalent disease that manifests drastically differently across individuals due to the interplay of multiple factors. Due to the disease’s multifaceted nature, the provision of safe, quality care within cancer is... Continue Reading →

How can we study cancer more accurately?

Reading time: 3 minutes Rachel Cherney If you have read other articles on Oncobites, you know that cancer is a collection of many diseases, and these diseases are complex. Cancer cells don’t live on their own; rather, they live among the normal tissue cells, immune cells, and bacteria in your body. Additionally, cancer cells can... Continue Reading →

The Power of Timing in Immunotherapy

Reading time: 3 minutes Natasha Vinod In 2018, the Nobel Prize in Physiology or Medicine was awarded to the inventors of immune checkpoint blockade therapy, a “game-changing” technology that initiated a paradigm shift in cancer management. Checkpoint blockade therapy works by unleashing the immune surveillance against cancer by blocking the “natural brakes” (checkpoints) in the... Continue Reading →

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